Can Creatine Help in the Fight Against Alzheimer's?

Could a popular workout supplement be the key to combating Alzheimer’s? Emerging research on creatine might change our perspective on cognitive health.

A recent study suggests creatine—the well-known supplement for strength and muscle—could play a role in the battle against Alzheimer’s. The primary focus in Alzheimer’s prevention has been to stop the buildup of amyloid-β plaques in the brain. One promising approach is improving “brain energy metabolism,” which declines before Alzheimer’s symptoms appear. Creatine may help by supplying energy to brain cells, supporting their normal function. As Alzheimer’s progresses, brain cells struggle with energy production, and creatine could act as a potential aid here.

In studies on mice, creatine helped address this energy issue, potentially reducing plaque buildup. Although animal studies don’t always translate directly to humans, these results are intriguing. Creatine is one of the most researched supplements, and the last decade has highlighted its cognitive benefits, such as improving memory and fighting cognitive decline.

Not to mention, creatine is also proven to enhance physical performance. As research grows, creatine is looking more and more like an excellent foundational supplement for nearly anyone.